In this article, we talked about the effects of PRP and PRF therapies in the dental sphere, with Dr. Elena Alecu, dentist and owner of the Aesthetic Dental Care dental clinic in Bucharest.
Various processes, such as PRP (Platelet Rich Plasma) and PRF (Platelet Rich Fibrin), offer new perspectives in dental treatments. Human blood contains a lot of components with healing properties, and because our body prefers natural healing, these processes become much easier. Both technologies are commonly used for surgical procedures in the medical and dental fields, especially in oral and maxillofacial surgery, plastic surgery and sports medicine. The key purpose behind using these technologies is to extract all the elements from a blood sample and use them to improve healing and promote tissue regeneration.
Platelet-rich fibrin, meaning (PRF) is the newer and simpler of the two. PRF is a substance that is extracted from the blood. It is derived from the concentration of the patient’s blood platelets. PRF possesses amazing natural healing properties and is completely in line with the holistic approach to oral health. The process involves collecting the blood and centrifuging it, which leads to the formation of the fibrin membrane by natural polymerization. PRF includes platelets, leukocytes and fibrin matrix and can be used alone or in addition to other biomaterials without inflammatory reactions.
The success rate of this process depends on the time interval between blood collection and centrifugation. The formed fibrin membrane helps to stimulate the release of many growth factors that are involved during wound healing, facilitating tissue regeneration, reducing inflammation, preventing bacterial, fungal or other infections, etc … PRF not only accelerates the healing process, but it also helps to heal wounds to a much greater extent than a wound left to heal on its own.
Benefits of PRP and PRF in dentistry

Below are mentioned some of the key benefits of PRF in dentistry:
✔ PRF helps restore bone around a dental implant by attracting osteoblasts (bone-forming cells) to the area of interest.
✔ Helps preserve the alveolar ridge.
✔ PRF stimulates the formation of new bone and helps to heal periodontal defects, thus improving the health of teeth.
✔ PRF is useful in oral cancer because it can reconstitute bone defects after surgery.
✔ PRF helps to regenerate the gums by increasing the volume of the gums.
✔ PRF heals the edges of the mucosa (soft tissues) by joining them.
✔ PRF has antibacterial properties, thus helping to prevent and treat infections.
✔ PRF accelerates wound healing.
✔ According to some studies, PRF is probably the only material that can enlarge the floor of the maxillary sinus.
✔ PRF reduces osteitis (bone inflammation) by up to 90%.

Platelet-rich plasma (PRP), on the other hand, aims to regenerate tissues and heal wounds in a variety of dental and oral surgical procedures, such as tooth removal, dental implants, bone grafts, periodontitis, and more. Today, PRP has become a very popular process in the dental field because it plays an important role in the patient’s recovery process after oral surgery. In simple terms, PRP is plasma with a high concentration of platelets that are usually found in the blood. The process involves drawing blood from the patient, centrifuging it into a platelet-rich plasma fragment.
It is loaded with high concentrations of growth factors that are directed to the site of the bone defect or other regions that need healing. PRP allows our body to take advantage of normal healing pathways at an increased rate. During the healing process, the body transfers a number of cells to the affected area (injury) to begin the healing process. Thus, this therapy involves injecting platelet concentrations into a specific damaged area of the human body to promote tissue repair and accelerate healing.

Below are mentioned are some of the key benefits of PRP in dentistry:
✔ PRP helps to increase tissue synthesis due to its growth factors, resulting in faster tissue regeneration.
✔ PRP can be prepared simultaneously during surgery by a trained dental specialist. So don’t waste time.
✔ Can be easily purchased.
✔ PRP is quite easy to handle, as it actually improves the ease of application of bone replacement materials.
✔ PRP not only helps to stimulate bone growth for dental implants, but can also be beneficial in other forms of restorative dentistry procedures, such as closing a split lip, repairing defects caused by tooth removal, or removing cysts or fistulas.
✔ PRP has many benefits in the treatment of periodontal disease (periodontitis) and gingivitis, through accelerated healing and reduction of inflammation.
Benefits of PRP and PRF in dentistry
Conclusion:
In the field of dentistry, as well as in the wider medical sector, there is a remarkable value placed on rapid healing. The faster a patient recovers after surgery, the lower the risk of infection and other serious complications. Both platelet-rich fibrin (PRF) therapies and platelet-rich plasma (PRP) therapies are perfect for rapid recovery after certain dental procedures. However, it is a good idea to consult with your surgeon and / or primary care physician to determine if PRF or PRP is right for you or not.